VALTREX by a elongated way reduced the venture of transmit herpes infectivity to a heterosexual partner by way of compare to placebo. Results from this become wallow in be nearly new to stay a topical sticky label suggestion surrounded by desire of VALTREX in the retrenchment in risk of conveyance of genital herpes when used in coincidence beside safer femininity run through.
This new indication have been agreed in the USA, Australia and Finland.
The transmission gain knowledge of with VALTREX published in the maximum recent edition of NEJM be a randomized, double-blind, placebo-controlled trial involving 1,484 tough, heterosexual, monogamous duo in 21 country.
The opening endpoint of the study was to assessment the reduction in risk of transmission of suggestive genital herpes (signs or symptom of GH confirmed with a lab test) to an uninfected partner with trot through of suppressive psychotherapy with VALTREX.
The study show that once-daily suppressive therapy with VALTREX 500 mg caplets reduced the risk of transmission of symptomatic genital herpes through 75 percent versus placebo (0.5 percent vs 2.2 percent).
In tallying up, suppressive therapy with VALTREX reduced the risk of overall acquirement of the virus (with or penniless symptoms confirmed by a lab test) by 48 percent versus placebo (1.9 percent vs. 3.6 percent).
In addition, VALTREX significantly reduced the signs of recurrences in the gangrenous partner versus placebo, standardized with erstwhile study.
Throughout the eight-month study, all couples be counsel by safer sex practices in any way study visit. The moral values of safer sex practices were (1) to overcome sexual setup when the infected partner have any symptoms of genital herpes and (2) consistent and true use of condoms during all sexual contacts.
The most widely report subdivision effects in the study were headache (VALTREX 29%, placebo 26%), nasopharyngitis (VALTREX 16%, placebo 15%), and upper respiratory infection (VALTREX 9%, placebo 10%). The effect of VALTREX on transmission of genital herpes has not been verified in immunocompromised individuals or same-sex couples.
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